Fig. 5.

IFNα modulates the CD8⁺ T cell-surface glycome. Heat-map depicting normalized lectin-binding intensity of CD8⁺ T cell-surface proteins isolated from CD8⁺ T cells before and five weeks during Peg-IFNα2a treatment. Heat colors show standardized Z-scores; red indicates higher binding, and blue indicates lower binding. Top half lists glycan structures whose levels decreased by IFNα treatment; bottom half lists glycan structures whose levels increased by IFNα treatment. Wilcoxon signed-rank tests. Nominal p values and corrected FDR are displayed. N = 8. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)