Table 1.
Clinical characteristics of the patients from multiple institutions.
| Characteristics | TCGA n=502 | GSE11969n=90 | GSE13213 n=117 | GSE30219 n=83 | GSE31210 n=226 | GSE41271 n=180 | Independentn=102 |
|---|---|---|---|---|---|---|---|
| Age, year | |||||||
| Median (IQR) | 66 (13.8) | 62.0 (12.0) | 61.0 (13.0) | 60.0 (14.0) | 61.0 (10.0) | 63.9 (13.8) | 60.0 (9.0) |
| Gender | |||||||
| Male | 231 (46.0%) | 47 (52.2%) | 60 (51.3%) | 65 (78.3%) | 105 (46.5%) | 91 (50.6%) | 56 (54.9%) |
| Female | 271 (54.0%) | 43 (47.8%) | 57 (48.7%) | 18 (21.7%) | 121 (53.5%) | 89 (49.4%) | 46 (45.1%) |
| Smoking history | |||||||
| Yes | 416 (82.9%) | 45 (50.0%) | 61 (52.1%) | – | 111 (49.1%) | – | 61 (59.8%) |
| No | 72 (14.3%) | 45 (50.0%) | 56 (47.9%) | – | 115 (50.9%) | – | 41 (40.2%) |
| NA | 14 (2.9%) | 0 (0.0%) | 0 (0.0%) | – | 0 (0.0%) | – | 0 (0.0%) |
| TNM stage | |||||||
| I and II | 388 (77.3%) | 65 (72.2%) | 92 (78.6%) | 83 (100.0%) | 226 (100.0%) | 129 (71.7%) | 80 (78.4%) |
| III and Ⅳ | 105 (20.9%) | 25 (27.8%) | 25 (21.4%) | 0 (0.0%) | 0 (0.0%) | 51 (28.3%) | 22 (21.6%) |
| NA | 9 (1.8%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) |
| OS state | |||||||
| Alive | 320 (63.7%) | 50 (55.6%) | 68 (58.1%) | 40 (48.2%) | 191 (84.5%) | 111 (61.7%) | 78 (76.5%) |
| Death | 182 (36.3%) | 40 (44.4%) | 49 (41.9%) | 43 (51.8%) | 35 (15.5%) | 69 (38.3%) | 24 (23.5%) |
Data are n (%). IQR, interquartile range; NA, not available; OS, overall survival.