Table 3.
Univariable and multivariable Cox regression analysis of the TNF family-based signature and survival in TCGA dataset.
| Univariable analysis |
Multivariable analysis |
|||||
|---|---|---|---|---|---|---|
| Variable | HR | 95%CI | P value | HR | 95%CI | P value |
| Age | ||||||
| ≥60 or <60 | 1.1575 | 0.7957–1.6838 | 0.4445 | |||
| Gender | ||||||
| Male or Female | 1.1568 | 0.8401–1.5928 | 0.3722 | |||
| Smoking history | ||||||
| Yes or No | 1.0374 | 0.6532–1.6476 | 0.8763 | |||
| T stage | ||||||
| 1, 2, 3 or 4 | 1.5458 | 1.2602–1.8961 | <0.0001 | 1.2142 | 0.9556–1.5428 | 0.1122 |
| Lymphatic metastasis | ||||||
| Yes or No | 2.4053 | 1.7466–3.3124 | <0.0001 | 1.6476 | 1.0696–2.5381 | 0.0235 |
| TNM stage | ||||||
| I, II, III or Ⅳ | 1.5587 | 1.3381–1.8156 | <0.0001 | 1.2344 | 0.9670–1.5757 | 0.0908 |
| ERFR status | ||||||
| MUT or WT | 1.4658 | 0.9584–2.2418 | 0.0777 | |||
| KRAS status | ||||||
| MUT or WT | 1.2159 | 0.8598–1.7195 | 0.2689 | |||
| Risk score | ||||||
| High or low | 2.0558 | 1.4802–2.8554 | <0.0001 | 2.0003 | 1.4146–2.8285 | 0.0001 |
Abbreviations: HR, hazard ratio; CI, confidence interval; WT, wild-type; MUT, mutation.