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Growth inhibition of P. falciparum. Dose-dependent effect of (A) dichloroacetic acid, (B) sirolimus, (C) metformin, (D) lonidamine, and (E) 2-deoxy-D-glucose on P. falciparum in vitro assays. Data was obtained by flow cytometry and the inhibition of parasite growth was standardized with CQ-treated results and then calculated with respect to infected but untreated RBCs. Each concentration was tested in triplicate and data represent mean ± SEM of three independent experiments.
