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. 2020 Apr 15;44(9):1629–1637. doi: 10.1007/s00264-020-04552-7

Table 4.

Overview of the diagnostic parameters (with 95% confidence intervals) of joint fluid culture and multiplex PCR

Test True positive False positive True negative False negative Sensitivity Specificity PPV NPV LR+ LR-
Joint fluid culture 10 1 10 5 0.67 (0.23, 0.63) 0.91 (0.59, 1.00) 0.91 (0.59, 1.00) 0.67 (0.38, 0.88) 7.33 (1.09, 49.16) 0.37 (0.17, 0.77)
Joint fluid multiplex PCR 12 0 11 3 0.8 (0.52, 0.96) 1.0 (0.69, 1.0) 1.0 (0.74, 1.0) 0.77 (0.46, 0.95) n/a 0.2 (0.07, 0.55)

PPV positive predictive value; NPV negative predictive value; LR+ positive likelihood ratio; LR- negative likelihood ratio