Table 3.
The 5-year C-statistic (95% CI) results of models trained on only AREDS or only AREDS2, and validated on the combined AREDS/AREDS2 test sets (601 participants), without using genotype information.
| Models | Trained on AREDS | Trained on AREDS2 |
|---|---|---|
| Late AMD | ||
| Deep features/survival | 85.7 (85.5,85.9) | 83.9 (83.7,84.1) |
| DL grading/survival | 84.7 (84.5,84.9) | 82.1 (81.8,82.3) |
| Geographic atrophy | ||
| Deep features/survival | 89.3 (89.1,89.5) | 84.7 (84.4,85.0) |
| DL grading/survival | 90.2 (90.0,90.4) | 85.2 (84.9,85.5) |
| Neovascular AMD | ||
| Deep features/survival | 79.6 (79.3,80.0) | 74.0 (73.6,74.5) |
| DL grading/survival | 76.6 (76.2,76.9) | 75.5 (75.1,75.9) |