Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Aug 27;11:4306. doi: 10.1038/s41467-020-18060-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 1 — a Sites of 13 metastases sampled during the autopsy and the anterior chest wall cutaneous primary melanoma. b Axial CT imaging from the brain, chest and abdomen before (left) and after (right) whole brain radiotherapy (imaging 5 weeks apart). Brain CT images represent the following metastatic sites (from top to bottom); right superior frontal gyrus, right frontal pole, left superior parietal, left posterior parietal and right brain vertex (the latter corresponding to the ‘right parietal’ sample labelled in the remainder of the text). Chest/abdomen CT images represent the following metastatic sites (from top to bottom); right lobe of liver, peripancreatic/greater omentum (corresponding to the ‘greater omentum’ sample labelled in the remainder of the text) and right lower lung. c Histological analyses (Hematoxylin-eosin images), from top left to bottom right; primary melanoma from the anterior chest wall, distant metastasis from; the left upper lobe of the lung, right frontal gyrus of the brain and right superior parietal lobe of the brain. Morphological appearances differ across the tumours, including varying cellular morphology and pigmentation. One representative region from each tumour sample is shown. The thick white line represents 100 µm in 40-fold magnification.