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. 2020 Aug 28;130:110627. doi: 10.1016/j.biopha.2020.110627

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© 2020 The Author(s)

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 2 — Dose-dependent ameliorative effects of CoQ10 on PM intoxication in the liver. A: Control saline group and B: CoQ10 group, show normal liver histology. C: PM-exposed rat shows fatty degeneration (signet cells) and vacuolation of hepatocytes, prominent Kupffer cells, and dilatation of central veins and the portal vein with severe lymphocytic infiltration. D: PM + CoQ10 L group demonstrates mild fatty degeneration and inflammatory cell infiltration. E: PM + CoQ10 H group shows remarkable improvement in liver histology (PV, portal vein; CV, central vein; H&E X400).