Figure 6.

Effect of SeNPs on cell apoptosis and caspase activities: (a) SeNP-induced apoptosis in BRL cells by flow cytometric analysis. Data presented are representative of flow cytometric experiments conducted in triplicate. (b) The apoptosis rate of BRL cells treated with different concentrations (ranging from 0.1 to 48 μM) of SeNPs for 24 h. (c) Analysis of caspase family activities (% of control) in SeNP-induced apoptosis in BRL cells. Data are expressed as the mean ± SD, n = 5. ^∗, ^∗∗, and ^∗∗∗ indicate significant difference as compared with the control (P < 0.05, 0.01, and 0.001 respectively).