Table 2.
Effect of SeNPs on antioxidant capacity in serum.
| Control | SeNPs | |||
|---|---|---|---|---|
| 2 mg Se/kg BW | 4 mg Se/kg BW | 8 mg Se/kg BW | ||
| SOD (U/mL) | 142.04 ± 6.48 | 153.39 ± 9.71 | 138.88 ± 10.78 | 128.11 ± 11.08 |
| MDA (nmol/mL) | 6.26 ± 0.54 | 6.1 ± 0.58 | 6.51 ± 0.62 | 7.79 ± 1.24∗ |
| GSH-Px (U/mL) | 1162.3 ± 70.28 | 1139 ± 108.74 | 1149.3 ± 129.43 | 1093.9 ± 85.19 |
| CAT (U/mL) | 0.90 ± 0.24 | 2.26 ± 0.63∗∗ | 2.95 ± 0.77∗∗∗ | 1.90 ± 0.67∗ |
| T-AOC (U/mg) | 2.72 ± 0.17 | 2.10 ± 0.41 | 2.22 ± 0.44 | 1.82 ± 0.26∗ |
| T-GSH (mg/L) | 45.20 ± 2.00 | 43.34 ± 4.84 | 42.77 ± 2.88 | 42.35 ± 2.2 |
| GSSH (mg/L) | 14.23 ± 0.95 | 14.63 ± 1.68 | 16.47 ± 0.99∗ | 20.03 ± 1.75∗∗∗ |
| GSH (mg/L) | 16.09 ± 0.93 | 20.11 ± 6.22 | 16.94 ± 1.64 | 13.51 ± 1.25∗ |
| ASA (U/g of protein) | 564.61 ± 5.96 | 579.93 ± 16.72 | 597.09 ± 17.07 | 426.1 ± 55.53∗∗∗ |
| IHR (U/g of protein) | 1331 ± 13.36 | 1342.8 ± 16.64 | 1316.2 ± 66.67 | 1295.5 ± 54.05 |
| H2O2 (mmol/L) | 28.18 ± 3.37 | 29.43 ± 5.58 | 40.09 ± 1.41∗∗∗ | 56.22 ± 4.73∗∗∗ |
Data are presented as the mean ± SD, n = 10. Control means the control treatment (without SeNP administration). ∗, ∗∗, and ∗∗∗ indicate significant difference as compared with the control treatment (P < 0.05, 0.01, and 0.001 respectively). SOD: superoxide dismutase; MDA: malondialdehyde; GSH-Px: glutathione peroxidase; CAT: catalase; T-AOC: total antioxidation capability; T-GSH: total glutathione; GSSH: oxidized glutathione; GSH: reduced glutathione; ASA: the abilities of antisuperoxide anion; IHR: inhibition of hydroxy radical.