Table 7.
Serum levels of IL-6, IL-12, TNF-α, and IFN-γ in mice (N = 10).
| Group | IL-6 (pg/mL) |
IL-12 (pg/mL) |
TNF-α (pg/mL) |
IFN-γ (pg/mL) |
|---|---|---|---|---|
| Normal | 24.97 ± 1.41d | 155.90 ± 8.07d | 17.27 ± 1.59d | 13.65 ± 1.01d |
| Model | 209.69 ± 9.97a | 822.17 ± 19.89a | 132.95 ± 8.29a | 84.49 ± 4.33a |
| Silymarin | 82.20 ± 2.57c | 352.09 ± 14.76c | 45.67 ± 2.38c | 37.11 ± 2.79c |
| SPL | 137.59 ± 5.36b | 627.25 ± 23.98b | 96.97 ± 7.32b | 60.58 ± 2.60b |
| SPH | 86.56 ± 2.46c | 369.57 ± 20.38c | 48.15 ± 2.45c | 42.71 ± 3.65c |
Values presented are the mean ± standard deviation (N = 10/group). Sample data in each group come from normal distribution, and the difference in variance between the two groups was significant (P > 0.05). a-dMean values with different letters over the bar are significantly different (P < 0.05) according to Tukey's honestly significant difference. Normal: untreated mice; model: CCl4-treated mice; SPL: 100 mg/kg Shoumei polyphenols and CCl4-treated mice; SPH: 200 mg/kg Shoumei polyphenols and CCl4-treated mice; silymarin: 200 mg/kg silymarin and CCl4-treated mice. IL-6: interleukin 6; IL-12: interleukin 12; TNF-α: tumour necrosis factor alpha; IFN-γ: interferon gamma.