Table 4.
Clinical measures at baseline, 6 weeks, and 12 weeks: community team sample.
| Scale and visit | CareLoop enhanced monitoring, mean (SD) | Management as usual, mean (SD) | Adjusted mean differencea | 95% CI |
P value, 2-tailed |
|
| PANSSb Total | ||||||
|
|
Baseline | 72.73 (11.71) | 78.32 (19.02) |
|
|
|
|
|
Weeks 6 | 69.47 (17.43) | 72.68 (22.53) | 1.30 | –8.98 to 11.58 | .80 |
|
|
Week 12 | 57.84 (14.23) | 68.59 (22.22) | –5.83 | –14.14 to 2.48 | .16 |
| PANSS Positive | ||||||
|
|
Baseline | 19 (4.22) | 19.36 (6.12) |
|
|
|
|
|
Weeks 6 | 16.42 (5.67) | 17.41 (6.65) | –0.95 | –3.91 to 2.01 | .52 |
|
|
Week 12 | 14.11 (4.10) | 17.18 (6.27) | –3.04 | –5.49 to –0.59 | .02 |
| PANSS Negative | ||||||
|
|
Baseline | 16.09 (4.21) | 18.77 (5.52) |
|
|
|
|
|
Weeks 6 | 15.42 (4.50) | 17.32 (6.12) | 0.004 | –2.83 to 2.92 | .98 |
|
|
Week 12 | 13.47 (4.58) | 16.45 (6.10) | –0.76 | –3.36 to 1.85 | .56 |
| PANSS General | ||||||
|
|
Baseline | 37.64 (7.49) | 40.18 (10.13) |
|
|
|
|
|
Weeks 6 | 37.63 (10.12) | 37.95 (11.46) | 1.43 | –4.51 to 7.36 | .63 |
|
|
Week 12 | 30.26 (8.55) | 34.95 (11.15) | –2.67 | –7.46 to 2.13 | .27 |
| ERSc Total | ||||||
|
|
Baseline | 86.73 (5.59) | 83.27 (6.53) |
|
|
|
|
|
Weeks 6 | 85.74 (5.69) | 83.68 (8.16) | 0.13 | –4.18 to 4.43 | .95 |
|
|
Week 12 | 86.26 (6.15) | 85.91 (8.07) | –1.26 | –5.80 to 3.29 | .58 |
| EQ5Dd Total | ||||||
|
|
Baseline | 8.09 (2.81) | 8.64 (3.09) |
|
|
|
|
|
Weeks 6 | 6.91 (3.53) | 8.23 (3.16) | 1.00 | –0.78 to 2.79 | .26 |
|
|
Week 12 | 6.45 (3.49) | 7.00 (2.31) | 0.33 | -1.35 to 0.83 | .20 |
| CDSe Total | ||||||
|
|
Baseline | 5.82 (4.16) | 8.5 (5.86) |
|
|
|
|
|
Weeks 6 | 6.63 (4.21) | 6.73 (4.46) | 1.60 | –0.486 to 3.67 | .13 |
|
|
Week 12 | 4.21 (3.03) | 6.27 (4.38) | –0.85 | –2.94 to 1.25 | .42 |
| GAFf | ||||||
|
|
Baseline | 42.38 (12.04) | 38.4 (6.42) |
|
|
|
|
|
Weeks 6 | 44.47 (13.29) | 41.91 (16.25) | –0.11 | –9.40 to 9.17 | .98 |
|
|
Week 12 | 48.47 (11.75) | 45.14 (18.93) | –1.09 | –10.05 to 7.00 | .80 |
aFollow-up differences adjusted for baseline scores.
bPANSS: Positive and Negative Syndrome Scale
cERS: Empowerment Rating Scale
dEQ5D: EuroQol-5D
eCDS: Calgary Depression Scale
fGAF: Global Assessment of Functioning