Table 1.

Top 10 Hub Genes With Higher Degree Scores.

Gene symbol	Functions	Degree
ASPM	Cell cycle, spermatogenesis, regulation of meiotic cell cycle, protein binding, positive regulation of neuroblast proliferation	45
DLGAP5	Protein binding, cell cycle, positive regulation of mitotic metaphase/anaphase transition, cell population proliferation	45
AURKA	ATP binding, cell cycle, G2/M transition of mitotic cell cycle, histone serine kinase activity	45
TPX2	Cell cycle, protein kinase binding, regulation of signal transduction by p53 class mediator, importin-alpha family protein binding	45
BUB1B	Cell cycle, apoptotic process, ubiquitin-dependent protein catabolic process, anaphase-promoting complex-dependent catabolic process	45
CCNB2	Cell cycle, protein kinase activity, cyclin-dependent protein serine/threonine kinase regulator activity, mitotic nuclear envelope disassembly	45
CDC45	DNA replication initiation, cell cycle, mitotic DNA replication preinitiation complex assembly, replication fork protection complex	45
PBK	Mitotic cell cycle, nucleotide binding, negative regulation of protein phosphorylation, negative regulation of stress-activated MAPK cascade	44
NUF2	Cell cycle, protein binding, mitotic spindle organization, attachment of mitotic spindle microtubules to kinetochore	44
BUB1	Kinase activity, cell cycle, apoptotic process, cell population proliferation	44