Table 3.
Univariate and Multivariate Analyses of Clinicopathologic Factors in Patients With HCC With Respect to OS.
| Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
| P value | HR (95% CI) | P value | ||
| Sex | Male vs female | .566 | ||
| Age | ≥46.5 vs <46.5 | .852 | ||
| HBV | HBV vs others | .889 | ||
| AFP levels | ≥20 ng/mL vs <20 ng/mL | .013 | 2.37 (0.72-7.78) | .154 |
| Tumor numbers | Single vs multiple | .137 | ||
| Vascular invasion | Present vs absent | .954 | ||
| Differentiation | ES III-IV vs ES Ⅰ-Ⅱ | .534 | ||
| BUB1B | High vs low | <.001 | 6.03 (1.82-19.99) | .003 |
| CD8 | High vs low | .012 | 0.87 (0.26-2.89) | .824 |
Abbreviations: HCC, hepatocellular carcinoma; HR, hazard ratio; OS, overall survival.