Table 4.
Univariate and Multivariate Analyses of Clinicopathologic Factors in Patients With HCC With Respect to DFS.
| Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
| P value | HR (95% CI) | P value | ||
| Sex | Male vs female | .804 | ||
| Age | ≥46.5 vs <46.5 | .14 | ||
| HBV | HBV vs others | .531 | ||
| AFP levels | ≥20 ng/mL vs <20 ng/mL | .01 | 2.47 (0.79-7.74) | .122 |
| Tumor numbers | Single vs multiple | .08 | ||
| Vascular invasion | Present vs absent | .084 | ||
| Differentiation | ES III-IV vs ES Ⅰ-Ⅱ | .69 | ||
| BUB1B | High vs low | .008 | 6.426 (2.22-18.64) | .001 |
| CD8 | High vs low | .098 | ||
Abbreviations: HCC, hepatocellular carcinoma; HR, hazard ratio; DFS, disease-free survival.