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. 2020 Jul 31;22(4):3151–3160. doi: 10.3892/mmr.2020.11396

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Copyright: © Guan et al.

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Figure 1. — ICAII pretreatment attenuates MIRI. (A) Representative images of hematoxylin and eosin staining in MIRI model rats following the treatment with various doses of ICAII (10, 20 or 30 mg/kg). Magnification, ×200; scale bar, 25-µm. Arrows indicate lesions and myocardial fiber rupture. (B) Damage scores of the severity of myocardial injury from part (A). Serum levels of (C) CK-MB and (D) LDH in each group. n=6. Data are presented as the mean ± SD. *P<0.05 vs. SO group; ^#P<0.05 vs. IR group. MIRI, myocardial ischemia and reperfusion injury; ICAII 10/20/30, 10/20/30 mg/kg icariside II; SO, sham-operated; CK-MB, creatine kinase-myocardial band; LDH, lactate dehydrogenase.