Skip to main content
. 2020 Aug 11;22(4):3245–3254. doi: 10.3892/mmr.2020.11427

Figure 2.

Figure 2.

Inhibition of TMPO-AS1 suppresses cell proliferation in CRC cells. (A) Knockdown of TMPO-AS1 represses TMPO-AS1 expression in SW480 and HCT15 cells. TMPO-AS1 knockdown suppresses cell proliferation in (B) SW480 and (C) HCT15 cells. (D) Cyclin D1, p21 and p27 protein expression levels assessed using western blotting in SW480 and HCT15 cells transfected with si-NC and si-TMPO-AS1. Inhibition of lncRNA TMPO-AS1 reduced cyclin D1 protein and enhanced p21 and p27 protein expression in (E) SW480 and (F) HCT15 cells. *P<0.05 vs. si-NC. CRC, colorectal cancer; si, short interfering; lnc, long non-coding; OD, optical density; NC, negative control; AS, antisense.