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. 2020 Aug 11;22(4):3245–3254. doi: 10.3892/mmr.2020.11427

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Copyright: © Zhao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Knockdown of TMPO-AS1 reduces cell migration and invasion in CRC cells. TMPO-AS1 knockdown suppressed (A) cell migration and invasion in (B) SW480 cells. TMPO-AS1 knockdown suppressed (C) cell migration and invasion in and (D) HCT15 cells. (E) Western blotting results of MMP-2, MMP-9 and MMP-14 expression levels in SW480 and HCT15 cells transfected with si-NC and si-TMPO-AS1. The protein expression of MMP-2, MMP-9 and MMP-14 was inhibited by TMPO-AS1 knockdown in (F) SW480 and (G) HCT15 cells. *P<0.05 vs. si-NC. si, short interfering; NC, negative control; MMP, matrix metalloproteinase; AS, antisense.