Figure 2.

Scatter plot and ROC curves for HCC and HC detection using AFP. (A) Scatter plot showing the serum AFP concentration of individuals with NED, HC and HCC. ROC curves for AFP sensitivity in detecting (B) HCC vs. NED, (C) HC vs. NED and (D) HCC vs. HC. The threshold (cutoff value) for AFP (dotted line) was set at 20 µg/l (log value at 1.30). Bars represent the mean ± 95% CI. AFP, α-fetoprotein; ROC, receiver operating characteristic; HCC, hepatocellular carcinoma; HC, hepatic cirrhosis; NED, no evidence of disease; AUC, area under the curve.