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. 2020 Jul 28;22(4):2810–2816. doi: 10.3892/mmr.2020.11375

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — miR-130a knockdown increases the sensitivity of acute myeloid leukemia cells to Adr. (A) The Cell Counting Kit-8 assay was performed to detect the viability of transfected HL-60 cells. The invasive ability of HL-60 cells was (B) determined using Transwell assays (magnification, ×200) and (C) quantified. (D) Reverse transcription-quantitative PCR was performed to measure the expression of miR-130a in HL-60 cells. **P<0.001 vs. the negative inhibitor group. ^##P<0.001 and ^#P<0.05 vs. inhibitor group. ^{^^}P<0.001 vs. negative inhibitor + Adr group. miR, microRNA; Adr, Adriamycin; Con, control; OD, optical density.