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Rats were injected intraperitoneally with 2 mg/kg LPS to induce a pneumonia model, and were then treated with UCF-101. The protein expression of HtrA2 in (A) cytoplasm and (B) mitochondria was detected using western blotting. Data are expressed as mean ± standard deviation (n=8). ***P<0.001 vs. control, ###P<0.001 vs. LPS+DMSO group. LPS, lipopolysaccharide; UCF-101, 5-[5-(2-nitrophenyl)furfuryl iodine]-1,3-diphenyl-2-thiobarbituric acid; HtrA2, high-temperature requirement A2.
