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. 2020 Jul 15;22(4):2723–2732. doi: 10.3892/mmr.2020.11343

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Copyright: © Zou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Expression of miR-15b-5p and its association with overall survival of patients with THCA. (A) Expression of miR-15-5b-5p was lower in patients with THCA (n=509) compared with healthy controls (n=58) according to starbase2.0 database. **P<0.01 vs. healthy controls. (B) Reverse transcription-quantitative PCR analysis identified the downregulation of miR-15b-5p in THCA cells compared with normal thyroid epithelial cells. All experiments were repeated three times. **P<0.01, vs. Nthy3 cells. (C) Patients with low expression of miR-15b-5p had a poorer prognosis compared with patients with high expression of miR-15b-5p (log rank, P<0.01). miR, microRNA; THCA, thyroid carcinoma.