Table II.

Effect of GI on body weight and organ indexes.

		3.5% dextran sulfate sodium
				Gl, g/kg
Variable	Control	Model	Sulfasalazine, 0.6 g/kg	1.0	2.0	4.0
Body weight, g
Day 1	22.8±0.2	22.6±0.4	22.3±0.4	22.5±0.3	22.6±0.4	22.6±0.3
Day 7	22.4±0.3	20.3±0.3a	20.2±0.3	20.5±0.4	20.3±0.3	20.5±0.3
Day 14	24.4±0.3	20.6±0.8b	21.2±0.5	21.4±0.7	21.6±0.3	21.2±0.7
Day 21	25.4±0.4	20.8±0.8b	22.1±0.4	22.3±0.5	22.9±0.3d	22.0±0.5
Day 28	24.3±0.4	21.2±0.5b	22.1±0.3	22.7±0.5d	23.4±0.3d	21.5±0.3
Organ index, %
Spleen	0.25±0.05	0.56±0.10c	0.45±0.05d	0.49±0.14	0.44±0.10d	0.38±0.11e
Liver	3.72±0.31	4.34±0.24a	4.32±0.13	3.95±0.44d	3.79±0.40d	3.58±0.27e
Kidney	1.16±0.05	1.03±0.05a	1.13±0.06d	1.10±0.10	1.11±0.05d	1.01±0.07

Data were analyzed using a one-way ANOVA and are expressed as mean ± SEM (n=8).

^aP<0.05

^bP<0.01

^cP<0.001 vs. control mice

^dP<0.05

^eP<0.01 vs. DSS-induced UC mice. GI, Gloeostereum incarnatum.