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. 2020 Aug 5;22(4):3418–3428. doi: 10.3892/mmr.2020.11420

Table III.

Effect of GI on inflammatory factors of colon tissues of mice with ulcerative colitis.

3.5% dextran sulfate sodium

GI, g/kg

Inflammatory factors Control Model SASP, 0.6 g/kg 1.0 2.0 4.0
IL-1β, pg/mgprot 45.7±3.9 60.0±3.5a 44.1±3.1d 48.4±1.4c 42.2±3.8c 39.7±3.7d
IL-2, pg/mgprot 158.1±9.4 219.1±14.6a 153.8±11.9c 130.2±11.0d 149.5±16.4c 128.4±10.1d
IL-6, pg/mgprot 61.6±3.7 83.7±6.3a 54.5±8.2c 57.3±1.4c 62.1±6.8 50.0±4.8d
IL-12, pg/mgprot 37.3±2.6 57.2±6.3a 31.9±3.9d 30.5±2.0d 39.6±2.0c 27.8±2.1d
TNF-α, pg/mgprot 407.5±21.9 489±22.2a 429.0±28.9 374.5±27.2c 358.0±43.1c 337.5±14.6d
TNF-β, pg/mgprot 78.6±7.8 119.8±11.5b 62.9±7.7d 70.1±4.1d 83.6±10.9c 63.3±4.4d
IFN-α, pg/mgprot 19.7±1.6 28.8±2.6b 16.3±1.9d 20.7±1.2c 20.2±1.6c 17.2±1.8d
IFN-γ, pg/mgprot 72.4±6.6 126.6±14.8b 72.9±9.5d 75.3±5.4d 84.2±5.5c 69.8±7.0c

Data were analyzed using a one-way ANOVA and are expressed as mean ± SEM (n=8).

a

P<0.05

b

P<0.01 vs. control mice

c

P<0.05

d

P<0.01 vs. DSS-induced UC mice. GI, Gloeostereum incarnatum; IL, interleukin; TNF, tumor necrosis factor; IFN, interferon.