Table IV.

Effect of GI on oxidative factors in serum and colon tissues of mice with ulcerative colitis.

A, Serum
		DSS
				GI, g/kg
Oxidative factors	CTRL	Model	SASP, 0.6 g/kg	1.0	2.0	4.0
SOD, U/ml	99.7±3.3	81.7±2.6c	94.8±3.1e	83.9±3.1	93.8±2.2e	98.2±1.9f
CAT, U/ml	26.8±0.9	21.9±1.1b	28.1±1.6e	24.7±1.7	29.5±1.7e	25.7±0.5d
ROS, U/ml	177.1±3.1	174.2±3.9	165.6±2.8	167.3±5.7	172.4±2.1	179.9±0.7
NO, µmol/l	14.0±0.6	17.8±0.8b	14.3±0.6d	15.3±0.8d	15.5±0.8d	15.1±0.4d
B, Colon
		DSS
				GI, g/kg
Oxidative factors	CTRL	Model	SASP, 0.6 g/kg	1.0	2.0	4.0
SOD, U/mgprot	152.0±9.6	104.5±9.1b	145.0±11.2d	113.8±3.7	119.7±8.6	142.4±4.3d
CAT, U/mgprot	31.3±2.2	21.4±2.1a	27.8±0.9d	22.2±0.6	25.3±1.9	22.2±1.4
ROS, U/mgprot	310.7±23.9	418.2±33.7a	308.5±22.7d	292.2±19.3d	310.3±13.2d	284.1±13.0d
NO, µmol/gprot	13.8±1.1	21.9±2.8a	11.5±1.9e	11.6±0.9d	12.0±1.7d	8.0±0.5e

Data were analyzed using a one-way ANOVA and are expressed as the mean ± SEMs (n=8).

^aP<0.05

^bP<0.01

^cP<0.001 vs. control mice

^dP<0.05

^eP<0.01

^fP<0.001 vs. DSS-induced UC mice. GI, Gloeostereum incarnatum; CTRL, control; DSS, dextran sulfate sodium.