TABLE 4.
Genes required for maintenance of [ARG8m] mtDNA. The yeast deletion collection was treated as outlined in Fig. 3A, and mutants showing an instable mtDNA phenotype were confirmed by DAPI staining. This table is an excerpt of Table S6. Genes with known functions in arginine biosynthesis or mating and dubious ORFs were excluded from this list.
| Standard name | ORF | Standard name | ORF | Standard name | ORF |
|---|---|---|---|---|---|
| mtDNA metabolism | |||||
| MGM101 | YJR144W | MIP1 | YOR330C | RIM1 | YCR028C-A |
| Mitochondrial transcription | |||||
| MTF1 | YMR228W | RPO41 | YFL036W | ||
| Mitochondrial translation and RNA maturation | |||||
| AEP3 | YPL005W | MRPL17 | YNL252C | MSW1 | YDR268W |
| ATP22 | YDR350C | MRPL20 | YKR085C | MSY1 | YPL097W |
| DIA4 | YHR011W | MRPL23 | YOR150W | PET123 | YOR158W |
| IMG1 | YCR046C | MRPL27 | YBR282W | PET130 | YJL023C |
| MRP17 | YKL003C | MRPL35 | YDR322W | RML2 | YEL050C |
| MRP20 | YDR405W | MRPL37 | YBR268W | RRG8 | YPR116W |
| MRP21 | YBL090W | MRPL49 | YJL096W | RSM18 | YER050C |
| MRP4 | YHL004W | MRPL51 | YPR100W | RSM19 | YNR037C |
| MRP51 | YPL118W | MRPS12 | YNR036C | RSM23 | YGL129C |
| MRP7 | YNL005C | MRPS16 | YPL013C | RSM24 | YDR175C |
| MRPL10 | YNL284C | MRPS35 | YGR165W | RSM27 | YGR215W |
| MRPL11 | YDL202W | MSK1 | YNL073W | SWS2 | YNL081C |
| MRPL16 | YBL038W | MST1 | YKL194C | ||
| Respiratory chain components and assembly factors | |||||
| COX5A | YNL052W | ||||
| Mitochondrial fusion | |||||
| FZO1 | YBR179C | PCP1 | YGR101W | ||
| MGM1 | YOR211C | UGO1 | YDR470C | ||
| Other mitochondrial function | |||||
| MDJ1 | YFL016C | OCT1 | YKL134C | PPA2 | YMR267W |
| Vacuole-related function | |||||
| VPS33 | YLR396C | ||||
| Other function | |||||
| HPR1 | YDR138W | RPP2A | YOL039W | UAF30 | YOR295W |
| Unknown function | |||||
| LCL1 | YPL056C | SOV1 | YMR066W | ||