Skip to main content
. 2020 Aug 7;22(4):3191–3200. doi: 10.3892/mmr.2020.11423

Figure 2.

Figure 2.

Effect of porcine serum on liver fibrosis. As liver fibrosis progressed, the expression of (A) Col IV, (B) PIIINP and (C) HA in the serum was measured. #P<0.05, ##P<0.01 vs N; *P<0.05, **P<0.01 vs. M. The liver (D) Hyp content and (E) 11β-HSD1 enzyme activity. ##P<0.01 vs. N; **P<0.01 and *P<0.05 vs. M. Protein expression levels were (F) determined by western blotting and semi-quantified for (G) α-SMA, (H) 11β-HSD1 and (I) CTGF. #P<0.05, ##P<0.01 and ###P<0.001 vs. N; *P<0.05, **P<0.01 and ***P<0.001 vs. M. Col IV, type IV collagen; PIIINP, N-terminal pro-peptide of collagen type III; HA, hyaluronic acid; N, normal control group; M, model group; M+I, 11β-HSD1 inhibitor (BVT.2733) group; Hyp, hydroxyproline; 11β-HSD1, 11β-hydroxysteroid dehydrogenase 1; α-SMA, α-smooth muscle actin; CTGF, connective tissue growth factor.