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. 2020 Aug 11;22(4):3117–3126. doi: 10.3892/mmr.2020.11426

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Copyright: © Shi et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Effects of LPS and/or apoM on serum IL-6 and IL-10 levels. Mice (n=6 per group) were randomly assigned to receive intraperitoneal injections of 0.9% saline (100 µl) or LPS (5 or 10 mg/kg in 100 µl saline) 3 times, once every 24 h. (A and B) Effects of LPS and/or apoM on the levels of serum IL-6 and IL-10 in apoM^−/− and apoM^+/+ mice. (C-F) Effects of cross interaction between apoM and LPS on serum IL-6 and IL-10 levels in 5- and 10 mg/kg-LPS groups. Data are presented as the means ± standard error or the mean. *P<0.05, **P<0.01, ***P<0.001 and ****P<0.0001. LPS, lipopolysaccharide; apoM, apolipoprotein M; IL, interleukin.