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. 2020 Aug 7;22(4):3255–3262. doi: 10.3892/mmr.2020.11422

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Copyright: © Jiang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Effects of FZ on the mRNA expression levels of ASC, TXNIP, NLRP3, caspase-1 and TRX. Reverse transcription-quantitative PCR was performed after cells were pretreated with Res for 2 h or co-cultured with FZ and HG for 48 h. (A) NLRP3, (B) ASC, (C) caspase-1, (D) TXNIP and (E) TRX mRNA expression. Data are presented as the mean ± standard deviation. *P<0.05 vs. the normal glucose group; ^#P<0.05 vs. the HG group. FZ, FPS-ZM1; ASC, apoptosis-related speck-like protein containing CARD; TXNIP, thioredoxin-interacting protein; NLRP3, nucleotide-binding oligomerization domain-like receptor protein 3; TRX, thioredoxin; HG, high glucose; Res, resveratrol.