Table 3:
Multivariable Logistic Regression of Persistent Postoperative Gabapentinoid Use
| Characteristic | Odds Ratio (95% CI) | P-Value |
|---|---|---|
| Age | ||
| 18-29 | 0.57 (0.36-0.90) | <0.05 |
| 30-39 | 0.73 (0.59-0.89) | <0.05 |
| 40-49 | 0.83 (0.72-0.96) | <0.05 |
| 50-59 | 1 [Reference] | - |
| 60-64 | 1.00 (0.85-1.15) | 0.85 |
| Female | 1.09 (0.97-1.23) | 0.17 |
| Median Household Income | ||
| <60,000 | 1.12 (0.96-1.31) | 0.16 |
| 60,000-69,999 | 1 [Reference] | - |
| 70,000-79,999 | 0.99 (0.83-1.18) | 0.88 |
| 80,000-89,999 | 0.88 (0.67-1.15) | 0.34 |
| ≥90,000 | 1.25 (1.08-1.44) | <0.05 |
| Charlson Comorbidity Index | 1.11 (1.06-1.17) | <0.05 |
| Diabetes | 1.38 (1.19-1.61) | <0.05 |
| Region | ||
| South | 1 [Reference] | - |
| North Central | 0.91 (0.79-1.05) | 0.18 |
| Northeast | 0.81 (0.68-0.96) | <0.05 |
| West | 0.83 (0.69-1.00) | 0.05 |
| Insurance | ||
| PPO | 1 [Reference] | - |
| Comprehensive | 1.31 (1.04-1.65) | <0.05 |
| HMO | 0.95 (0.79-1.14) | 0.59 |
| Point of Service | 1.15 (0.95-1.38) | 0.15 |
| Other | 0.84 (0.69-1.03) | 0.10 |
| Mental Health Disorders | ||
| Adjustment | 1.38 (1.02-1.88) | <0.05 |
| Anxiety | 1.24 (1.03-1.50) | <0.05 |
| Disruptive | 0.75 (0.46-1.22) | 0.25 |
| Mood | 1.09 (0.93-1.29) | 0.30 |
| Suicide of Self-Harm | 0.84 (0.23-3.03) | 0.78 |
| Personality | 3.98 (1.64-9.68) | <0.05 |
| Psychosis | 1.17 (0.42-3.26) | 0.76 |
| Alcohol or Substance Abuse | 1.20 (0.80-1.80) | 0.38 |
| Other | 0.71 (0.46-1.12) | 0.14 |
| Pain Disorders | ||
| Arthritis | 1.13 (1.01-1.27) | <0.05 |
| Back | 1.41 (1.24-1.60) | <0.05 |
| Neck | 1.03 (0.89-1.20) | 0.67 |
| Other | 1.24 (1.09-1.40) | <0.05 |
| Preoperative Gabapentinoid Use | 21.40 (19.16-23.91) | <0.05 |