Table 3.

Listing of the factors found with an influence on fatal disease courses

Reference	Lifestyle factors	Demographic factors	Preexisting comorbidities	Developed comorbidities	Clinical factors	Symptoms
[15]				Heart damage Kidney damage Liver damage	Decrease albumin Increased PCT Increased neutrophils Increased C-reactive protein Increased cTnI Increased d-Dimer Increased LHD Decreased lymphocyte level
[21]		Higher age Male gender
[22]		Age > 65 years		Kidney impairment	Leucocyte count > 4 × 109/L Lymphocyte < 1.5 × 109/L Increased serum creatinine baseline Increased serum creatinine peak Increased blood urea nitrogen (BUN) Increased proteinuria Increased hematuria
[23]				Thrombocytopenia	Decreased platelet count (40% decrease in mortality risk for every 50 × 109/L increase) Dynamic change of platelets
[24]	Higher BMI	Higher age	Hypertension Diabetes Coronary heart disease		Neutrophil to lymphocyte ratio (NLR) 8% higher risk per unit increase Respiratory rate > 30 bpm Increased neutrophil Increased ALT Increased creatinine Increased prothrombin Increased C-reactive protein Increased procalcitonin
[26]			Hypoproteinemia Cholestasis Acute liver injury		CT abnormalities Patchy shadows Ground glass opacities Consolidation Interlobular septal thickening Higher CT value
[28]			Diabetes
[30]		Higher age Male gender
[32]			Kidney disease	Acute kidney injury	Elevated baseline serum creatinine Elevated baseline blood urea nitrogen (BUN) Proteinuria Hematuria
[34]		Age > 65	Coronary heart f Disease Cardiovascular disease		PCT > 0.5 ng/ml AST > 40U/l	Dyspnea
[37]		Higher age	Chronic illness Cerebrovascular disease	Acute Respiratory Distress Syndrome Hospital acquired infection organ function damage (kidney, cardiac, liver) Hypoxemia	Low ratio partial pressure oxygen (PaO2) to FiO2
[38]		Higher age	Hypertension Coronary heart disease	Heart injury Cardiac death	Increased NT-proBNP Increased myohemoglobin Increased CK-MB Increased hs-TnI Increased blood urea Increased creatinine Increased white blood cell count Increased CRP Increased procalcitonin Decreased lymphocyte Higher diastolic blood pressure
[39]		Higher age Male gender	Hypertension Cardiovascular disease Hypercholesterolemia Diabetes