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. 2020 Jul 23;5(14):e134888. doi: 10.1172/jci.insight.134888

Figure 5. Inhibition of the miR-183 cluster improves the angiogenic potential of adult MCECs.

Figure 5

(A) Graph showing that inhibition of the miR-183 cluster improves migration of adult mouse cardiac endothelial cells (MCECs, green line) compared with adult MCECs transfected with control mimic (black line). (B) Bar graph showing increased migration rate of adult MCECs after miR-183 cluster inhibition. (C) Bar graph showing increased tube-like structures formation in adult MCECs transfected with miR-183 cluster or miR-96 or miR-183 inhibitors. (D) Bar graph showing a higher number of EdU+ cells (increased proliferation) in adult MCECs after inhibition of the miR-183 cluster or miR-96 or miR-183. n = 3/group (C); n = 4/group (B and D). *P < 0.05, **P < 0.01 vs. control anti-miR (Student’s t test or 1-way ANOVA with Bonferroni’s post hoc test. Data are shown as mean ± SEM.