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. 2020 Aug 27;10(8):e034626. doi: 10.1136/bmjopen-2019-034626

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Analysis of progression-free survival for patients with favourable-risk disease. (A) Network diagram: the size of every treatment node corresponds to the number of randomly assigned patients. The width of the lines is proportional to the number of trials. (B) Forest plot, with sunitinib as the comparator. (C) Ranking of treatments. Rankograms were drawn according to distribution of the ranking probabilities. Ranking indicates the probability to be the best treatment, the second best, the third best, and so on, in terms of progression-free survival (PFS), among the 13 treatments. Numbers in parentheses indicate 95% credible intervals. AVE_AXI, avelumab plus axitinib; AXI, axitinib; BEV_IFN, bevacizumab plus interferon; EVE, everolimus; IFN, interferon; NIV_IPI, nivolumab plus ipilimumab; PAZ, pazopanib; PEM_AXI, pembrolizumab plus axitinib; PLA, placebo; SOR, sorafenib; SUN, sunitinib; TEM_BEV, temsirolimus plus bevacizumab; TIV, tivozanib.