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. 2020 Aug 27;8(1):e001600. doi: 10.1136/bmjdrc-2020-001600

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.

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Associations between glycated hemoglobin (HbA1c) and incidence of common cancers in the UK Biobank. HRs from Cox proportional hazards models, adjusted for age at study entry, sex (except sex-specific cancers), ethnicity, deprivation, body mass index, physical activity, cardiovascular disease, diagnosed diabetes, smoking status, alcohol consumption, use of oral contraceptives and hormone replacement therapy (postmenopausal breast only), and processed meat and fruit and vegetable intake (colorectal only). Reference HbA1c=5.4% (35 mmol/mol). Results shown including (left) and excluding (right) those with diagnosed diabetes at baseline. Significance tests include p overall for test of overall association, p non-linear for test of linearity, p non-PH for test of proportional hazards.