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. 2020 Aug 27;8(2):e001141. doi: 10.1136/jitc-2020-001141

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.

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Diagram of the main cellular and molecular interactions implemented in the model (modified from30 33). APC, antigen-presenting cell; IL2, interleukin-2; PD-L1, programmed cell death ligand 1; TCE, T cell engager.