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. 2020 May 8:ciaa546. doi: 10.1093/cid/ciaa546

Figure 1.

Figure 1.

Concentration–response curves for chloroquine’s effect on the LPS-triggered production of TNF-α, IL-6, CCL2, and CCL3. Human lung explants from 6 to 7 patients were stimulated with LPS in the absence or presence of chloroquine (0.001–1 mM). *P < .05, **P < .01, ***P < .001 compared with LPS alone. Abbreviations: CCL2, monocyte chemoattractant protein 1; CCL3, macrophage inflammatory protein 1α; IL-6, interleukin-6; LPS, lipopolysaccharide; TNF-α, tumor necrosis factor α.