Table 1.
Baseline Patients Characteristics on Admission
| Total | Supportive Care | Remdesivir | ||
|---|---|---|---|---|
| n = 224 | n = 125 | n = 99 | P Value | |
| Age | 59.00 (50.00–68.00) | 60.00 (50.00–68.00) | 58.00 (50.00–68.00) | .52 |
| Gender | .44 | |||
| Female | 74 (33.0) | 44 (35.2) | 30 (30.3) | |
| Male | 150 (67.0) | 81 (64.8) | 69 (69.7) | |
| Race | .65 | |||
| Asian | 2 (0.9) | 1 (0.8) | 1 (1.0) | |
| Black or African American | 30 (13.4) | 20 (16.0) | 10 (10.1) | |
| Hispanic or Latino | 98 (43.8) | 50 (40.0) | 48 (48.5) | |
| Other/unknown | 12 (5.4) | 7 (5.6) | 5 (5.1) | |
| White or Caucasian | 82 (36.6) | 47 (37.6) | 35 (35.4) | |
| Hypertension | 87 (38.8) | 55 (44.0) | 32 (32.3) | .075 |
| Heart disease | 49 (21.9) | 35 (28.0) | 14 (14.1) | .013 |
| Chronic pulmonary disease | 26 (11.6) | 15 (12.0) | 11 (11.1) | .84 |
| Diabetes | 60 (26.8) | 32 (25.6) | 28 (28.3) | .65 |
| Renal failure | 10 (4.5) | 7 (5.6) | 3 (3.0) | .36 |
| Liver disease | 9 (4.0) | 5 (4.0) | 4 (4.0) | .99 |
| Obesity | 103 (46.0) | 60 (48.0) | 43 (43.4) | .50 |
| Days from symptoms onset | 6.00 (3.00–8.00) | 6.00 (2.00–7.00) | 6.00 (3.00–8.00) | .59 |
| Baseline oxygen | .75 | |||
| Invasive mechanical ventilation | 43 (19.5) | 24 (19.7) | 19 (19.2) | |
| Low-flow supplemental oxygen | 108 (48.9) | 60 (49.2) | 48 (48.5) | |
| NIPPV or HFOD | 55 (24.9) | 28 (23.0) | 27 (27.3) | |
| Room air | 15 (6.8) | 10 (8.2) | 5 (5.1) | |
| Corticosteroidsa | 61 (27.2) | 34 (27.2) | 27 (27.3) | .99 |
| Hydroxychloroquine | 25 (11.2) | 20 (16.0) | 5 (5.1) | .010 |
| Convalescent plasma | 19 (8.5) | 16 (12.8) | 3 (3.0) | .009 |
| Weighted Elixhauser index (van Walraven) | .009 | |||
| <0 | 53 (23.7) | 24 (19.2) | 29 (29.3) | |
| 0 | 61 (27.2) | 27 (21.6) | 34 (34.3) | |
| 1–4 | 30 (13.4) | 21 (16.8) | 9 (9.1) | |
| ≥5 | 80 (35.7) | 53 (42.4) | 27 (27.3) |
Bold values: P < 0.05. Data are presented as No. (%) or median (interquartile range). Comorbidities were estimated using ICD-10 codes according to the Elixhauser Comorbidity Index.
Abbreviations: HFOD, high-flow oxygen devices; ICD-10, International Classification of Diseases, 10th Revision; NIPPV, noninvasive positive pressure ventilation.
aAt least 1 dose of dexamethasone, fludrocortisone, hydrocortisone, methylprednisolone, or prednisone.