Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Aug 13;6(2):veaa057. doi: 10.1093/ve/veaa057

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 3. — Heterogeneities in the dinucleotide composition of the SARS-CoV-2 genome. (A–C) Comparison of the dinucleotide and coding compositions of SARS-CoV-2 open reading frames (ORFs) for (A) CpG observed:expected (O:E) ratios, (B) UpA O:E ratios and (C) Codon pair bias (CPB) scores. Average scores across the genome are indicated using open circles. (D), Sliding window analysis of CpG content of SARS-CoV-2 (green line) and closely related bat (RaTG13; black line) and pangolin (purple line) isolates. The CpG O:E ratio of the 3′ end of the genome was measured in 100 nucleotide windows in 25 nucleotide increments. The mean of 1,163 complete genome sequences is presented for SARS-CoV-2.