Table 2. Sensitivity analyses for initial rSO2 and mean rSO2.

Outcomes	Excluding study	WMD and 95% CI	P-value	Heterogeneity (%)	P-value for heterogeneity
Initial rSO2 (%)	Ahn 2013	10.77 (6.02 to 15.52)	<0.001	74.0	0.002
	Genbrugge 2015	10.30 (5.44 to 15.16)	<0.001	76.1	0.001
	Fukuda 2014	10.27 (5.29 to 15.25)	<0.001	75.9	0.001
	Koyama 2013	9.91 (4.66 to 15.16)	<0.001	76.4	0.001
	Meex 2013	10.36 (5.75 to 14.97)	<0.001	76.1	0.001
	Ibrahim 2015	8.43 (5.96 to 10.90)	<0.001	0.0	0.961
	Prosen 2018	10.44 (5.24 to 15.64)	<0.001	64.9	0.014
Mean rSO2 (%)	Ahn 2013	14.02 (10.00 to 18.04)	<0.001	78.2	<0.001
	Parnia 2014	13.38 (9.70 to 17.06)	<0.001	75.7	<0.001
	Genbrugge 2015	14.65 (10.53 to 18.77)	<0.001	76.1	<0.001
	Singer 2014	14.79 (10.85 to 18.73)	<0.001	75.7	<0.001
	Parnia 2012	13.94 (10.06 to 17.82)	<0.001	78.1	<0.001
	Schewe 2014	14.40 (10.68 to 18.13)	<0.001	77.9	<0.001
	Ibrahim 2015	12.31 (9.83 to 14.78)	<0.001	31.4	0.167
	Parnia 2016	14.68 (10.56 to 18.79)	<0.001	75.2	<0.001
	Prosen 2018	13.98 (10.06 to 17.91)	<0.001	78.2	<0.001
	Singer 2018	14.79 (10.87 to 18.71)	<0.001	75.9	<0.001

*rSO2: regional cerebral oxygen saturation; WMD: weighted mean difference.