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. 2020 Aug 28;16(8):e1008766. doi: 10.1371/journal.ppat.1008766

Fig 3. YAP-1/YAP is activated during disruption of intestinal barrier induced by pathogens.

Fig 3

(A and B) P. aeruginosa (A) or S. Typhimurium (B) infection led to nuclear translocation of YAP-1::GFP in the intestine of worms. (C) Quantification of YAP-1 nuclear accumulation (n = 3 independent experiments, n = 100/condition). ***P < 0.001 relative to 0 h (One-way ANOVA followed by a Student-Newman-Keuls test). (D and E) The levels of phosphorylated YAP-1 were reduced in wild type (WT) worms after P. aeruginosa (D) or S. Typhimurium (E) infection. The blot is typical of three independent experiments. yap-1, yap-1(tm1416) mutants. (F) Quantification of the ratio of p-YAP-1 to total YAP-1. These results are means ± SD of three experiments. **P < 0.01 relative to 0 h (One-way ANOVA followed by a Student-Newman-Keuls test).