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. 2020 Aug 28;16(8):e1008766. doi: 10.1371/journal.ppat.1008766

Fig 7. PP2A is required for activation of YAP-1/YAP after knockdown of hmr-1 fed E. coli OP50.

Fig 7

(A) Knockdown of let-92, paa-1, and sur-6 suppressed the nuclear translocation of YAP-1/YAP in worms subjected to hmr-1 RNAi. (B) Quantification of YAP-1 nuclear accumulation (n = 3 independent experiments, n = 100/condition). ***P < 0.001 relative to empty vector (EV) (Two-sample t-test). (C) Knockdown of let-92, paa-1, and sur-6 restored the phosphorylation of YAP-1 in hmr-1 RNAi worms. The blot is typical of three independent experiments. (D) Quantification of the ratio of phosphorylated YAP-1 (p-YAP-1) to total YAP-1 (T-YAP-1). These results are means ± SD of three experiments. **P < 0.01 relative to EV (Two-sample t-test).