Table 2. Gene Ontology enrichment of suppressors of CDC5ΔC-AME1 and CDC5.
CDC5ΔC-AME1 suppressors: | ||
GO terms | Gene name | P-value |
Intracellular transport | PAC1, PAC11, SPC72, DYN1, AIM21, ARP1, GPA1 | 3.9E-04 |
Histone deacetylation | RXT3, HDA1, SET3, SIF2, HOS2, HOS4, RCO1 | 6.8E-04 |
RNA metabolism | 53 gene deletions or ts mutants* | 5.2E-04 |
Mediator complex | SRB5, MED4, CSE2, NUT1, BUD27, SOH1, MED8 | 6.8E-04 |
Set3 complex | HOS2, HOS4, SET3, SIF2 | 9.0E-04 |
CDC5 suppressors: | ||
GO terms | Gene name | P-value |
intracellular transport | KIP2, PAC1, PAC11, SPC72, DYN1, AIM21, ARP1, DYN3, NUM1, NDL1 | 2.3E-05 |
7-methylguanosine RNA capping | CTL1, SPT4, CEG1, STO1, TGS1 | 7.5E-04 |
Dynein complex | DYN3, PAC11, JNM1, DYN1, ARP1 | 9.0E-04 |
*See S4 Data for list of genes.