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. 2020 Aug 20;5(16):e138722. doi: 10.1172/jci.insight.138722

Figure 8. Targeted quantification LysoPCs in the CFBE41o- cells.

Figure 8

(A) LysoPC levels in lysates following treatment with the triple combination (VX-661/VX-445/VX-770) after 24 hours of incubation. The average level of the control group is represented by the dotted red line. §P < 0.05 compared with control, 1-way ANOVA test with Dunnett’s post hoc test. (B) LysoPC levels in the supernatants of the same CFBE41o- cells at 24 hours, following treatment with the triple combination. The average level in the medium at the beginning of the incubation is indicated by the dotted green line. Box-and-whiskers plot represent the median value (inner bar), the first and third quartile (box), and the minimum and maximum value (outer bars). Data represent mean ± SEM, n = 5. *P < 0.05 compared with control, 2-tailed t test.