Skip to main content
. 2020 Aug 28;6(35):eaba1394. doi: 10.1126/sciadv.aba1394

Table 1. Statistical models.

Model Criterion Predictors (within
subject)
Predictors (between
subject)
Covariates Random effects
Effects of APOE, subtask, and path distance on performance
1a Performance Subtask, outgoing
distance
APOE Age, sex Subject, site
1b Performance Subtask, incoming
distance
APOE Age, sex Subject, site
1c Performance Subtask, (outgoing and
incoming) path
distance, type of
distance
APOE Age, sex Subject, site
Effects of landmark and boundary
2a Performance Goal-to-boundary
distance
APOE Subject, site
2b Performance Goal-to-landmark
distance
APOE Subject, site
2c Distance to boundary APOE Subject, site
2d Distance to landmark APOE Subject, site
Effects of EC volume, APOE, subtask, and path distance on performance
3a Performance Subtask, outgoing
distance
APOE, relative EC
volume
Age, sex Subject
3b Performance Subtask, incoming
distance
APOE, relative EC
volume
Age, sex Subject
Effects of HC volume, APOE, subtask, and path distance on performance
4a Performance Subtask, outgoing
distance
APOE, relative HC
volume
Age, sex Subject
4b Performance Subtask, incoming
distance
APOE, relative HC
volume
Age, sex Subject
Effects of PC/RSC volume, APOE, subtask, and distance on performance
5a Performance Subtask, outgoing
distance
APOE, relative PC/RSC
volume
Age, sex Subject
5b Performance Subtask, incoming
distance
APOE, relative PC/RSC
volume
Age, sex Subject
Mechanistic model to explain path integration performance
6 Performance Subtask, incoming
distance
EC integrated path
representations during
incoming phase, HC
goal proximity
representations during
incoming phase, pmEC
GLRs, PC/RSC landmark
representations
Subject