Table 2.

Parametric analysis (P1): effects of threat features on brain activation

Cluster anatomy (manual labeling)	Cluster size	FWE p (cluster level)	Peak z score	Peak coordinates (MNI; mm)	Peak label (AAL)
Threat probability; negative linear effect
L middle frontal gyrus (dlPFC)	14	0.049	4.02	−33, 45, 30	Frontal_Mid_L
L putamen; L insula (anterior short gyrus)	17	0.015	3.97; 3.80	−20, 15, −3; −30, 18, −8	Putamen_L; Insula_L
R cerebellum	25	0.015	4.23	44, −47, −33	Cerebelum_Crus1_R
Threat magnitude; negative linear effect
L anterior limb of internal capsule/putamen	36	<0.001	4.41	−23, 15, 8	Putamen_L
L insula (posterior short gyrus)	16	0.042	4.29	−36, −2, 6	NA
R inferior frontal gyrus, opercular part (vIPFC)	16	0.042	4.28	42, 9, 27	Frontal_Inf_Oper_R
R cerebellum	784	<0.001	4.76	33, −53, −23	Cerebelum_6_R
	82	<0.001	4.50	18, −47, −18	Cerebelum_4_5_R
	56	<0.001	4.30	26, −62, −57	Cerebelum_8_R
	59	<0.001	4.12	9, −72, −26	Cerebelum_6_R
	53	<0.001	4.08	15, −66, −45	Cerebelum_8_R
	34	<0.001	3.92	29, −66, −27	Cerebelum_6_R
L cerebellum	33	<0.001	3.93	−30, −51, −23	Cerebelum_6_L
	16	0.008	3.67	−35, −63, −26	Cerebelum_6_L
Cerebellar vermis	18	0.021	3.76	−3, −59, −32	Vermis_9
L inferior temporal gyrus	17	0.030	3.88	−51, −62, −20	Temporal_Inf_L
Threat probability × magnitude; positive linear effect
L entorhinal cortex; L presubiculum and parasubiculum extending into CA1 (of aHC)	14	0.043	3.50	−16, −9, −27	ParaHippocampal_L
	12	0.002 (SVC)	3.50; 3.29	−17, −9, −27; −18, −14, −21	ParaHippocampal_L Hippocampus_L

Parametric modulating effects of threat probability, magnitude and their interaction on brain activation (Analysis P1). FWE-corrected results (p < .05) at cluster level (whole-brain + whole-brain/small volume corrected (SVC) for hippocampus), at a voxel-inclusion level inclusion threshold of p < 0.001. Manual labeling in comparison with schematic brain atlas (Mai et al., 2016). Automated labeling shows AAL (Tzourio-Mazoyer et al., 2002) peak labels verbatim.