. 2020 Aug 26;40(35):6748–6758. doi: 10.1523/JNEUROSCI.2732-19.2020

Table 5.

ROI analyses in aHC and amygdala

	F	df	p
aHC
A	8.76	1, 1214.6	0.003^**
TP²	5.46	1, 1208.2	0.020^*
TM²	14.22	1, 1210.1	<0.001^***
TP × H	5.65	1, 1208.0	0.018^*
TP² × A	5.50	1, 1208.9	0.019^*
TP × TM × H	7.30	1, 1208.0	0.007^**
TP × A × H	8.38	1, 1208.0	0.004^**
Amygdala
H	8.64	1, 1207.9	0.003^*
TP²	4.45	1, 1208.2	0.035^*
Anterior CA1
TP² × A	8.88	1, 1208.8	0.003^**
TP × TM × H	8.65	1, 1208.8	0.003^**
Anterior CA2/3
A	10.14	1, 1222.6	0.001^**
Basolateral amygdala
TM	6.26	1, 1210.9	0.012^*
H	11.13	1, 1207.5	<0.001^***
Centrocortical amygdala
H	6.81	1, 1208.1	0.009^**
TM²	9.28	1, 1208.4	0.002^**
TM² × A	6.77	1, 1208.1	0.009^**
Combined model: aHC + amygdala
A	9.91	1, 2434.9	0.002^**
ROI	13.61	1, 2433.9	<0.001^***
TM²	10.23	1, 2434.2	0.001^**
TP × H	6.05	1, 2433.9	0.014^*
A × ROI	7.87	1, 2433.9	0.005^**
TM² × ROI	4.98	1, 2433.9	0.026^*
TP × TM × H	6.82	1, 2433.9	0.009^**
TP × A × H	8.50	1, 2433.9	0.004^**
TP × H × ROI	4.39	1, 2433.9	0.036^*
TP × TM × H × ROI	4.37	1, 2433.9	0.037^*
TP × A × H × ROI	5.87	1, 2433.9	0.015^*
Combined model: anterior CA1 + anterior CA2/3
A × ROI	4.95	1, 2670	0.026^*

Main and interaction effects significant after Holm-Bonferroni correction (*p < 0.05; **p < 0.01; ***p < 0.001) from Analysis of Variance (ANOVA) of mixed effects model of estimated condition-by-condition BOLD response averaged across region-of-interest (entire/subregional amygdala and anterior hippocampus). Significant main and interaction effects from ANOVA of combined mixed effects model for amygdala vs. anterior hippocampus and anterior CA1 vs. anterior C2/3. Abbreviations: TP = threat probability, TM = threat magnitude, A = action, H = hemisphere, ROI = region-of-interest.