Table 2.
Predictors of Mortality, Low O2 Saturation, and Sepsis Among MSHS COVID-19 Patients
| Relative Odds of Deatha |
Relative Odds of Hypoxemia at Admissionb |
Relative Odds of Sepsis at Admissionc |
||||
|---|---|---|---|---|---|---|
| Variable | ORadj (95% CI) | Variable | ORadj (95% CI) | Variable | ORadj (95% CI) | |
| Sex: Male vs female | 1.37 (1.15-1.64) | Sex: Male vs female | 1.37 (1.13-1.66) | Sex∗ Agec | Females | Males |
| Age, y | Age, y | Age, y | ||||
| <40 | 1 (ref) | <40 | 1 (ref) | <40 | 1 (ref) | 3.50 (1.79-6.82) |
| 40-69 | 8.45 (3.43-20.81) | 40-69 | 2.14 (1.52-3.01) | 40-69 | 1.26 (0.78-2.05) | 1.84 (1.15-2.80) |
| ≥70 | 24.21 (9.83-59.63) | ≥70 | 2.90 (2.03-4.15) | ≥70 | 0.90 (0.56-1.46) | 1.05 (0.65-1.70) |
| History of CKD, y/n | 1.38 (1.10-1.73) | Race | Race | |||
| BMI ≥ 35 kg/m2, y/n | 1.53 (1.21-1.94) | White | 1 (ref) | White | 1 (ref) | |
| Black | 0.59 (0.45-0.77) | Black | 1.05 (0.85-1.30) | |||
| Other/unknown | 0.86 (0.67-1.10) | Other/unknown | 1.41 (1.17-1.70) | |||
| History of COPD, y/n | 1.62 (0.98-2.70) | History of cancer, y/n | 1.53 (1.17-2.00) | |||
| History of cancer, y/n | 1.44 (1.00-2.06) | History of hypertension, y/n | 0.88 (0.75-1.03) | |||
| BMI ≥ 35 | 1.72 (1.31-2.26) | |||||
CKD = chronic kidney disease.
Stepwise logistic regression model performed. Race, smoking status, hypertension, history of asthma, COPD, diabetes, HIV, cancer were originally included in the model and were removed; the final model was adjusted for sex, age, history of CKD, and BMI.
Stepwise logistic regression model performed. Smoking status, hypertension, asthma, CKD, and HIV were originally included in the model and were removed. The final model was sex, age, race, history of COPD, history of cancer, and BMI. Hypoxemia was defined as patients with ≤92% peripheral O2 saturation.
Stepwise logistic regression model performed. Smoking status, asthma, COPD, CKD, HIV, and obesity were originally included in the model and were removed. The final model was adjusted for sex∗age, age, race, history of cancer, and history of hypertension. The age∗sex interaction term (P < .05) and the sex and age group interaction terms (40-69 vs <40 years; P = .0182; ≥70 vs <40 years, P = .0018) were statistically significant.