Table 2. Characteristic oscillatory changes during dexmedetomidine-induced altered behavioral states.

Behavioral state	Slow-Delta	Alpha	Beta	Spindle activity
Wakefulness	minimal	absent	high	absent	Figure 2B,C,E,F Figure 4B
LOC	high with delay	transiently high	minimal	high
Unresponsiveness	high	low	absent	high
ROC	minimal*	high	absent	high
ROPAP	minimal	minimal	high	minimal
Arousal by external stimuli after LOC during dexmedetomidine infusion	minimal	transiently high	absent	NA	Figure 2H
Reversal by α2-adrenergic antagonist during dexmedetomidine infusion	minimal	absent	high	absent	Figure 5B,C,E,F,G

Note: The characteristic changes of the frequency band power and spindle activity are summarized for each behavioral endpoint. *The slow-delta power was diminished at ROC, but frequently reappeared through early recovery until ROPAP.