Figure 1. Microstructural alterations in contact athletes.

(A–E) Statistically significant white matter axial diffusivity (AD), mean diffusivity (MD), radial diffusivity (RD), and fractional anisotropy (FA) differences between contact athletes (during both the in- and off-season) and noncontact athletes during the in-season are shown in hot colors, including areas of the corpus callosum, cingulum, brainstem, superior longitudinal, and inferior occipital fasciculi (p < 0.001 unless otherwise indicated).