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. 2020 Jul 14;95(2):e140–e154. doi: 10.1212/WNL.0000000000009760

Figure 5. Percentage of annual volume and metabolic loss in patients with behavioral variant frontotemporal dementia (bvFTD) at mild (Clinical Dementia Rating [CDR] 0.5) and moderate (CDR 1–2) stages of the disease.

Figure 5

Results of robust linear mixed effect models comparing patients with bvFTD to cognitively normal (CN) participants for their changes in volume and metabolism in each brain region of the Harvard-Oxford atlas. Values represent the percentage of annual volume changes, with 95% Wald confidence intervals, in patients at mild (n = 10 and n visit = 22) and moderate (n = 20 and n visit = 58) stages of the disease compared to CN. Colors represent the significance of the results: orange: surviving Bonferroni correction for multiple comparisons (α = 0.05, p < 0.0009, 53 models considered); blue: p < 0.01 uncorrected; gray: p > 0.01.